Starting at Boonsboro and ending at Williamsport, the race is run over a variety of surfaces including roads, trails and dirt tracks. There are partial cut-offs at 8 checkpoints.
There are 14 fully stocked checkpoints with drinks, snacks and first aid supplies. Those reached in the latter stages of the event will offer hot drinks.
Bag transport to the finish line is provided. Personal listening devices are banned due to the dangerous footing of some sections of the Appalachian Trail. Crewing is permitted in the designated areas but pacing is not allowed.
